During last years many applications have been developed in the field of telemedicine. These prototypes have demonstrated their ability to provide medical users and patients with new capabilities making use of the Information and Communication Technologies. However most of the developed systems are not longer used after a test period. There are many factors which are related to the success/failure of these applications and services: two of them may be the absence of standardization in the systems and also the lack of an evaluation methodology.

In this presentation we will describe several examples of recent e-Health applications and services developed in our research group in Spain in different areas with the collaboration of several hospitals. The presentation will cover some telemedicine services in the field of electroencephalography, dermatology and cardiology, providing some insight on how they should be evaluated considering aspects such as e.g. viability and impact of the systems. Moreover, a description of a prototype implementation of the ISO/IEEE11073 standard for interoperability of medical devices will be presented in the context of a telemonitoring platform. The main open points to be considered in future e-Health use cases and scenarios in the evolution towards m-Health and u-Health will be also described.